Rudolf A de Boer Selected Research

Natriuretic Peptides

12/2023	Effect of Dapagliflozin Versus Placebo on Symptoms and 6-Minute Walk Distance in Patients With Heart Failure: The DETERMINE Randomized Clinical Trials.
1/2023	Association of Dapagliflozin vs Placebo With Individual Kansas City Cardiomyopathy Questionnaire Components in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction: A Secondary Analysis of the DELIVER Trial.
1/2023	Clonal haematopoiesis of indeterminate potential: associations with heart failure incidence, clinical parameters and biomarkers.
1/2023	Effect of dapagliflozin on health status and quality of life across the spectrum of ejection fraction: Participant-level pooled analysis from the DAPA-HF and DELIVER trials.
12/2022	Time to Clinical Benefit of Dapagliflozin in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction: A Prespecified Secondary Analysis of the DELIVER Randomized Clinical Trial.
12/2022	Efficacy and safety of dapagliflozin in patients with heart failure with mildly reduced or preserved ejection fraction by baseline glycaemic status (DELIVER): a subgroup analysis from an international, multicentre, double-blind, randomised, placebo-controlled trial.
11/2022	Estimated Long-Term Benefit of Dapagliflozin in Patients With Heart Failure.
2/2022	The year in cardiovascular medicine 2021: heart failure and cardiomyopathies.
10/2021	Circulating heart failure biomarkers beyond natriuretic peptides: review from the Biomarker Study Group of the Heart Failure Association (HFA), European Society of Cardiology (ESC).
3/2021	The Time Has Come to Explore Plasma Biomarkers in Genetic Cardiomyopathies.

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Rudolf A de Boer Research Topics

Disease

255	Heart Failure 05/2024 - 12/2002
50	Fibrosis (Cirrhosis) 01/2024 - 12/2003
38	Cardiomyopathies (Cardiomyopathy) 05/2024 - 11/2012
37	Myocardial Infarction 03/2024 - 04/2002
33	Cardiovascular Diseases (Cardiovascular Disease) 11/2023 - 05/2008
28	Neoplasms (Cancer) 03/2024 - 09/2009
25	Inflammation (Inflammations) 01/2023 - 09/2009
20	Atrial Fibrillation 08/2023 - 01/2010
19	Type 2 Diabetes Mellitus (MODY) 05/2024 - 12/2011
14	Heart Diseases (Heart Disease) 12/2023 - 05/2008
14	Obesity 10/2023 - 09/2010
12	Hypertension (High Blood Pressure) 12/2023 - 07/2007
11	Hypertrophy 10/2023 - 01/2012
10	Cardiac Arrhythmias (Arrythmia) 03/2024 - 04/2002
10	Stroke (Strokes) 03/2024 - 01/2010
10	Cardiomegaly (Heart Hypertrophy) 01/2023 - 06/2010
9	Chronic Renal Insufficiency 11/2023 - 12/2013
8	Diabetes Mellitus 08/2023 - 07/2010
7	Ischemia 11/2021 - 04/2002
6	Left Ventricular Dysfunction 01/2024 - 11/2012
6	Cardiotoxicity 06/2023 - 12/2018
6	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 02/2022 - 11/2012
6	Systolic Heart Failure 01/2021 - 08/2008
6	Body Weight (Weight, Body) 01/2020 - 09/2011
5	Chronic Obstructive Pulmonary Disease (COPD) 03/2024 - 01/2016
5	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 02/2023 - 01/2018
5	Reperfusion Injury 11/2019 - 12/2004
5	Infarction (Infarctions) 01/2016 - 08/2011
5	Myocardial Ischemia (Ischemic Heart Diseases) 01/2016 - 04/2006
4	Iron Deficiencies 08/2023 - 01/2018
4	Coronary Artery Disease (Coronary Atherosclerosis) 08/2023 - 09/2010
4	Atherosclerosis 01/2022 - 05/2011
4	Anemia 01/2015 - 03/2008
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 12/2023 - 01/2010
3	Albuminuria 12/2023 - 01/2016
3	Mitochondrial Diseases (Mitochondrial Disease) 08/2023 - 01/2020
3	Infections 01/2023 - 06/2015
3	Pulmonary Hypertension 01/2022 - 10/2015
3	Necrosis 01/2022 - 02/2009
3	Ventricular Remodeling 01/2022 - 02/2013

Drug/Important Bio-Agent (IBA)

77	Biomarkers (Surrogate Marker)IBA 05/2024 - 03/2010
67	dapagliflozinIBA 05/2024 - 11/2019
37	Galectin 3 (LGALS3)IBA 08/2023 - 09/2009
35	Natriuretic PeptidesIBA 12/2023 - 08/2008
29	Glucose (Dextrose)FDA LinkGeneric 05/2024 - 07/2010
27	Brain Natriuretic Peptide (Natrecor)FDA Link 05/2024 - 12/2002
24	Proteins (Proteins, Gene)FDA Link 02/2024 - 12/2010
21	phospholambanIBA 03/2024 - 11/2012
20	pro-brain natriuretic peptide (1-76)IBA 03/2024 - 01/2018
20	SodiumIBA 11/2023 - 12/2013
17	Sodium-Glucose Transport ProteinsIBA 05/2024 - 11/2019
12	Troponin T (Troponin T1)IBA 10/2022 - 05/2013
12	TroponinIBA 01/2022 - 06/2015
11	Sodium-Glucose Transporter 2 InhibitorsIBA 11/2023 - 11/2019
9	Vitamin D FDA LinkGeneric 01/2023 - 01/2011
9	Erythropoietin FDA Link 01/2016 - 12/2004
8	CreatinineIBA 03/2024 - 01/2010
8	DiureticsIBA 03/2024 - 01/2017
8	AlbuminsIBA 03/2024 - 04/2006
8	C-Reactive ProteinIBA 08/2023 - 04/2006
8	Angiotensin IIIBA 01/2022 - 04/2002
7	SymportersIBA 01/2022 - 01/2019
6	Metformin (Glucophage)FDA LinkGeneric 01/2015 - 08/2011
5	salicylhydroxamic acid (SHAM)IBA 02/2024 - 08/2008
5	Growth Differentiation Factor 15IBA 01/2022 - 09/2013
5	PotassiumIBA 01/2022 - 10/2014
5	ReninIBA 12/2019 - 09/2011
4	MicroRNAs (MicroRNA)IBA 01/2024 - 01/2016
4	CalciumIBA 12/2023 - 12/2010
4	Phosphotransferases (Kinase)IBA 10/2023 - 12/2010
4	CholesterolIBA 01/2022 - 05/2013
4	Trinitrotoluene (TNT)IBA 01/2022 - 02/2019
4	proenkephalinIBA 12/2021 - 08/2017
4	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2021 - 08/2008
4	CollagenIBA 01/2020 - 10/2004
4	empagliflozinIBA 01/2020 - 01/2019
4	LectinsIBA 09/2015 - 09/2009
4	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 03/2015 - 04/2012
3	Neprilysin (Neutral Endopeptidase)IBA 03/2024 - 12/2017
3	Angiotensin Receptors (Angiotensin II Receptor)IBA 03/2024 - 12/2017
3	SeleniumIBA 12/2023 - 01/2022
3	IronIBA 08/2023 - 01/2018
3	Triglycerides (Triacylglycerol)IBA 08/2023 - 03/2016
3	Therapeutic UsesIBA 01/2023 - 03/2008
3	LigandsIBA 01/2023 - 01/2022
3	Antihypertensive Agents (Antihypertensives)IBA 01/2023 - 01/2016
3	Messenger RNA (mRNA)IBA 01/2023 - 10/2013
3	Uric Acid (Urate)IBA 01/2023 - 01/2010
3	LDL CholesterolIBA 10/2022 - 09/2010
3	KetonesIBA 01/2022 - 01/2021
3	RNA (Ribonucleic Acid)IBA 01/2022 - 11/2021
3	Ketone BodiesIBA 01/2022 - 01/2021
3	apixabanIBA 10/2021 - 12/2011
3	HDL CholesterolIBA 05/2021 - 01/2018

Therapy/Procedure

67	Therapeutics 05/2024 - 01/2005
11	Drug Therapy (Chemotherapy) 03/2024 - 08/2009
5	Implantable Defibrillators (Implantable Cardioverter-Defibrillator) 03/2024 - 11/2012
4	Patient Readmission 10/2022 - 07/2010
4	Precision Medicine 01/2022 - 06/2018
3	Aftercare (After-Treatment) 01/2022 - 01/2017